Statistical analysis of functional connectivity (ROI-ROI)

Hi everyone,

I’m not sure if anyone would be able to help me out with this.

But here it goes:
I have a functional connectivity (correlation coefficient) matrix derived from fMRI . I have 5 Networks I’m looking at (i.e. DMN, FPN, SN, etc) - each of which have 10 ROIs’.

When I want to do a statistical analysis I don’t want to do an ROI-ROI t-test and then a post hoc and correct for the ROI’s. Instead I wanted to compare networks… and if there is a statistically significant difference between two networks, I want to do a post hoc test to see which pair of ROI’s contain the difference.

I hope that makes sense. Do you know if there’s any toolbox or command that may able to help with this?

I have a functional connectivity (correlation coefficient) matrix derived from fMRI . I have 5 Networks
I’m looking at (i.e. DMN, FPN, SN, etc) - each of which have 10 ROIs’.

Do you have a correlation matrix for each of those 5 networks or for all the 50 ROIs across the 5 networks?

I wanted to compare networks… and if there is a statistically significant difference between two networks,
I want to do a post hoc test to see which pair of ROI’s contain the difference.

It’s possible to try something as laid out here, but I may need more details about the data structure: https://afni.nimh.nih.gov/afni/community/board/read.php?1,159647,159647#msg-159647