Multiple comparison for multiple seeds in 3dClustSim


I estimated the seed-based functional connectivity analysis in multiple seeds (i.e. 10 seeds), and I have already estimated the 3dClustSim for the voxel-wise multiple comparisons.
I was wondering do I also need to do multiple comparisons for multiple seeds? (i.e. the corrected p-value from 3dClustSim divided by seeds number, 0.05/10)

Thanks a lot.

If you live in the conventional statistical framework, it is difficult to avoid the heavy penalty (and the watermark of 0.05/10). ROI-based analysis may help with the 10 seeds as part of the hierarchical model:

Previous discussion:,160410,160414