Group analysis using 3dLMEr and SPM contrast images

AFNI Message Board
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Hi there folks,

I could use some help with deciphering the appropriate AFNI group analysis program for a data set I’m working with.

My design is a two-group design, medicated vs undmedicated groups, with scanner, age, sex, and dosage (medicated group only) covariates and I’m ultimately interested in testing group differences in the different task trial types.

I have preprocessed task fmri data and have conducted the appropriate 1st level analyses in SPM. My question is if its possible to take the first level con_000*.nii images to 3dLMEr to perform group level analyses?

Any help on this would be greatly appreciated.

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if its possible to take the first level con_000*.nii images to 3dLMEr to perform group level analyses?

Almost all AFNI programs including 3dLMEr accept NIfTI files as input. Let us know if you encounter any issues.