I am transforming F- and t-statistic maps to z-statistic maps using 3dcalc. In some cases (when df1=1) I think that the z-statistic map resulting from the transformation of the F-statistic should be the same as the z-statistic map resulting from the transformation of the t-statistic. However, I tend to get slightly different results in such cases. I am wondering if this is due to numerical issues or if I make a mistake. Below the AFNI commands:
3dinfo stats.sub-CAS0001_REML+tlrc[0]
-- At sub-brick #0 'Full_Fstat' datum type is float: 7.54451e-11 to 65.7991
statcode = fift; statpar = 1 247
3dinfo stats.sub-CAS0001_REML+tlrc[2]
-- At sub-brick #0 'activation_stimulus#0_Tstat' datum type is float: -4.76188 to 8.11167
statcode = fitt; statpar = 247
3dcalc -a stats.sub-CAS0001_REML+tlrc[0] -expr 'cdf2stat(stat2cdf(a, 4, 1, 247, 0), 5, 0, 0, 0)' -prefix standardized_stats/zstat_from_Fstat.nii
3dinfo standardized_stats/zstat_from_Fstat.nii
-- At sub-brick #0 'Full_Fstat' datum type is float: -4.34628 to 7.5404
statcode = fift; statpar = 1 247
3dcalc -a stats.sub-CAS0001_REML+tlrc[2] -expr 'fitt_t2z(a, 247)' -prefix standardized_stats/zstat_from_tstat.nii
3dinfo standardized_stats/zstat_from_tstat.nii
-- At sub-brick #0 'activation_stimulus#0_Tstat' datum type is float: -4.65303 to 7.63014
statcode = fitt; statpar = 247
As you see, the minimum values in the z-statistic maps are -4.34628 and -4.65303, not quite the same. Is it a numerical issue?
I cannot offer an exact explanation for such discrepancies. One possibility is a data precision issue; if so, add option “-datum float” to your 3dcalc command and see if that makes any difference.
A side note: you can use “3dmerge -1zscore …” to the whole file, and it will convert all the statistics sub-bricks in the file to Z-stat (and keep anything else intact). At least it works for AFNI format. Not so sure about NIfTI files, though.
Thanks a lot for your response! So it looks like this is only a numerical issue. However, adding option “-datum float” to 3dcalc did not change the results. “3dmerge -1zscore” sounds like a very helpful command, but actually for my AFNI-format data it only works for the t-statistic map (brick [2]), not for the F-statistic map (brick [0]):
3dmerge -1zscore stats.sub-CAS0001_REML+tlrc[0]
3dinfo mrg+tlrc
++ 3dinfo: AFNI version=AFNI_16.2.02 (Jul 19 2016) [64-bit]
Dataset File: mrg+tlrc
Identifier Code: XYZ_PWSMDGionJcw1ZRWJwi0kA Creation Date: Wed Mar 14 00:52:12 2018
Template Space: TLRC
Dataset Type: Func-Bucket (-fbuc)
Byte Order: LSB_FIRST [this CPU native = LSB_FIRST]
Storage Mode: BRIK
Storage Space: 524,288 (524 thousand [kilo]) bytes
Geometry String: "MATRIX(2.999178,0,-0.103922,-94.31225,0.036819,-2.554494,2.327512,34.34985,0.05979,1.573074,3.779615,-124.6071):64,64,32"
Data Axes Tilt: Oblique (31.651 deg. from plumb)
Data Axes Approximate Orientation:
first (x) = Right-to-Left
second (y) = Posterior-to-Anterior
third (z) = Inferior-to-Superior [-orient RPI]
R-to-L extent: -94.312 [R] -to- 94.688 [L] -step- 3.000 mm [ 64 voxels]
A-to-P extent: -154.650 [A] -to- 34.350 [P] -step- 3.000 mm [ 64 voxels]
I-to-S extent: -124.607 [I] -to- 13.033 [S] -step- 4.440 mm [ 32 voxels]
Number of values stored at each pixel = 1
-- At sub-brick #0 'Full_Fstat' datum type is float: 8.67712e-06 to 7.63014
statcode = fizt
It is not important, but maybe you would see an explanation.
So it looks like this is only a numerical issue. However, adding option “-datum float” to 3dcalc did not change the results.
You can double check some voxels in the brain and make sure that those two files have roughly the same z-values.
“3dmerge -1zscore” sounds like a very helpful command, but actually for my AFNI-format data it only works for the
t-statistic map (brick [2]), not for the F-statistic map (brick [0]):
Actually it did. It does not change the labels, but it does convert all statistic values to z-values as shown in the sub-brick coding:
statcode = fizt
which indicates a Z-stat sub-brick.
The
National Institute of Mental Health (NIMH) is part of the National Institutes of
Health (NIH), a component of the U.S. Department of Health and Human
Services.