Dear afni experts,
In longitudinal studies, MRI and fMRI images of a subject at different time points were collected.
We can normalize the anatomical images independently as in cross-sectional studies.
However, this method neglect the within-subject information in spatial normalization.
There are longitudinal pipelines for morphology measures such as in freesurfer.
Do you think it is necessary to optimize the registration in longitudinal fMRI studies?
if so, is it possible to optimize the registration issue in longitudinal fMRI studies using existing tools in AFNI?
Thanks very much！