Dear experts,
I have a question related to 3dclustsim correction for a ROI analysis, I hope you may be able to advise me.
Next to a whole brain analyses, we have some hypotheses related to specific regions, so we plan to run some tests within (quite an extensive) ROI.
Is it necessary to apply the ROI mask to both 3dFWHMx and 3dClustSim commands? Or could I use the same acf values and/or cluster thresholds as for the whole brain analysis?
Thank you,
Kind regards, Rozemarijn
Hi Rozemarijn,
That might be a touchy subject these days, and one can imagine arguing either way. And along those lines, hopefully it would not matter much. I would be more inclined to estimate it at the whole brain level, which should be more robust, rather than making it dependent on the exact ROI chosen. You could use the values afni_proc.py already outputs. But again, one could argue the other way.
The National Institute of Mental Health (NIMH) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services.
Freedom of Information Act |
HHS Vulnerability Disclosure
National Institute of Mental
Health | National Institutes of Health | U.S.
Department of Health and Human Services |