1dGC.R Negative Path coefficient and T values

Dear Gang,

I am trying to use 1dGC.R in my study. I have run 1dGC with 4 ROIs. In subject level and group level analysis, I found that some path showed negative values. Does it mean that for the two time series, there is a lagged anti-correlation, such that higher activation in the first ROI is predicting lower activation in the second ROI with lagging?

In the group difference analysis, shall I do a statistical correction on those paths? (say FDR or Bonferroni)

Best,
Clive

Does it mean that for the two time series, there is a lagged anti-correlation, such that higher activation in the first ROI
is predicting lower activation in the second ROI with lagging?

Yes, that’s right.

In the group difference analysis, shall I do a statistical correction on those paths? (say FDR or Bonferroni)

No established approach to handling multiple comparisons in this case.